Notes: Data can also be arranged in index mode for two-way mixed-design ANOVA. To preform two-way mixed-design ANOVA, the data can be arranged as below The researcher record their weights every three months during the treatment program. 48 participants(24 male) take part in the study. Interpret results of the two-way mixed design ANOVAĪ researcher wants to know whether a treatment can help people lose weight.Perform the two-way mixed design ANOVA.Minimum Origin Version Required: OriginPro 2016 SR0 What you will learn It is ANOVA with one repeated-measures factor and one between-groups factor. The two-way mixed-design ANOVA is also known as two way split-plot design (SPANOVA).